Cutaneous necrotizing vasculitis in a patient with rheumatoid arthritis that developed after COVID-19: description of a clinical case

Abstract

The article discusses the pathogenesis and clinical manifestations of cutaneous vasculitis in rheumatoid arthritis (RA) and the role of autoimmune disturbances in the development of micro- and macrovascular thrombosis of the venous and arterial vessels caused by SARS-CoV-2 virus infection. A clinical case is described in which skin necrosis in the elbow joint area developed in a patient with a long-term course of RA after COVID-19. The process subsided against the background of treatment with an interleukin-6 inhibitor.

Keywords

• covid-19
• rheumatoid arthritis
• cutaneous vasculitis
• biologic disease-modifying antirheumatic drugs
• tumor necrosis factor-α inhibitors
• interleukin-6 inhibitors
• rituximab