Nature Communications (Sep 2020)

A trimeric CrRLK1L-LLG1 complex genetically modulates SUMM2-mediated autoimmunity

  • Yanyan Huang,
  • Chuanchun Yin,
  • Jun Liu,
  • Baomin Feng,
  • Dongdong Ge,
  • Liang Kong,
  • Fausto Andres Ortiz-Morea,
  • Julia Richter,
  • Marie-Theres Hauser,
  • Wen-Ming Wang,
  • Libo Shan,
  • Ping He

DOI
https://doi.org/10.1038/s41467-020-18600-8
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 15

Abstract

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MAPK signaling suppresses autoimmunity mediated by the SUMM2 receptor in Arabidopsis. Here Huang et al. show that a trimeric complex consisting of the GPI anchored protein LLG1, and the two receptor-like proteins LET1 and LET2, promotes activation of SUMM2 according to MAPK signaling status.