Nature Communications (May 2022)

Vinyl copolymers with faster hydrolytic degradation than aliphatic polyesters and tunable upper critical solution temperatures

  • Amaury Bossion,
  • Chen Zhu,
  • Léa Guerassimoff,
  • Julie Mougin,
  • Julien Nicolas

DOI
https://doi.org/10.1038/s41467-022-30220-y
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 15

Abstract

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The non-degradability of vinyl polymers has long limited their use in biomedical applications. In this article, the authors demonstrate a system based on acrylamide and cyclic ketene acetals to obtain copolymers with faster degradation rates for potential drug release and environmental applications.