A Review on (Hydro)Porphyrin-Loaded Polymer Micelles: Interesting and Valuable Platforms for Enhanced Cancer Nanotheranostics

Bruno  F. O. Nascimento; Nelson  A. M. Pereira; Artur  J. M. Valente; Teresa  M. V. D. Pinho e Melo; Marta Pineiro

doi:10.3390/pharmaceutics11020081

Pharmaceutics (Feb 2019)

A Review on (Hydro)Porphyrin-Loaded Polymer Micelles: Interesting and Valuable Platforms for Enhanced Cancer Nanotheranostics

Bruno F. O. Nascimento,
Nelson A. M. Pereira,
Artur J. M. Valente,
Teresa M. V. D. Pinho e Melo,
Marta Pineiro

Affiliations

Bruno F. O. Nascimento: CQC and Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal
Nelson A. M. Pereira: CQC and Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal
Artur J. M. Valente: CQC and Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal
Teresa M. V. D. Pinho e Melo: CQC and Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal
Marta Pineiro: CQC and Department of Chemistry, University of Coimbra, Rua Larga, 3004-535 Coimbra, Portugal

DOI: https://doi.org/10.3390/pharmaceutics11020081
Journal volume & issue: Vol. 11, no. 2
p. 81

Abstract

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Porphyrins are known therapeutic agents for photodynamic therapy of cancer and also imaging agents for NIR fluorescence imaging, MRI, or PET. A combination of interesting features makes tetrapyrrolic macrocycles suitable for use as theranostic agents whose full potential can be achieved using nanocarriers. This review provides an overview on nanotheranostic agents based on polymeric micelles and porphyrins developed so far.

Published in Pharmaceutics

ISSN: 1999-4923 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine: Pharmacy and materia medica
Website: http://www.mdpi.com/journal/pharmaceutics/

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