Risk factors in patients with angiographically severe coronary artery disease: differences by sex

Abstract

Introduction: Ischemic heart disease is the leading cause of death worldwide and it is important to establish the influence of risk factors on the severity of it. Objective: To determine the possible association of classic risk factors with angiographically severe coronary artery disease in both sexes. Methodologic design: Analytical, cross sectional study with 1000 patients randomly chosen those who underwent coronary angiography at the Institute of Cardiology and Cardiovascular Surgery of Habana in 2012. Demographic variables, cardio-vascular risk factors, coronary vessels affected and severity of these were studied. Chi square test for the quantification of the risk the odds ratio and logistic regression was used was used for the association of the variables. Results: The predominant age group in both sexes was 60 or more years. 32% of women were diabetic. Left main coronary was affected in 18% of women. 16.3% of the male population had three-vessel disease. Diabetes mellitus and obesity in-creased the risk of three-vessel disease in women (OR = 3.23 and OR = 4.9 respectively), also increased risk (OR = 1.2; p = 0.005) of developing severe ischemic heart disease (TCI and / or three-vessel disease) in females in univariate analysis and multivariate analysis (OR = 2.061; p = 0.012) by means of logistic regression. Conclusion: Diabetes mellitus increased the risk of angiographically severe coronary artery disease in women of this se-ries. Key words: Coronary artery disease, multivessels disease, left main coronary, risk factors

Keywords

• cardiopatía isquémica, enfermedad de múltiples vasos
• tronco coronario izquierdo, factores de riesgo