Características microbiológicas de infecciones en pacientes pediátricos con cáncer del eje cafetero colombiano, 2014-2016

Abstract

Objective: To describe microbiological characteristics of infections in pediatric patients with cancer in a reference center of the Colombian coffee region, 2014-2016. Materials and methods. Cross-sectional, descriptive study including underaged oncological inpatients managed in a reference institution in Colombia; who have been dated an infection with a subsequent antibiogram done. The collection sheet validated by experts is reported through WHONET 5.6. Descriptive statistical analyzes were performed with STATA 14.2, official version. Results. 2691 cultures from 596 patients were included. 53.86% were male, the mean age was 8.86 years. 76.89% of the cultures were performed in the hospitalization area. 74.36% of the cultures were blood, with 22.04% positive reports. The second sample with the highest number of cultures was urine with 16.16%, with 25.75% positive cultures. The highest percentage of positive cultures was for feces and biopsies with 71.21% and 53.13%, respectively. An overall positivity rate of 25.75% was presented. The three main microorganisms isolated were Gram negative. The most isolated microorganisms were K. pneumoniae (24.4%), E. coli (21.06%) and P. aeruginosa (17.46%). Conclusion. Infection pattern similar to the one reported in adults, being the Gram-negatives the most prevalent agents. We recommend establishing antibiotic dispensing policies thus achieving microbiological risk control and improving epidemiological surveillance.

Keywords

• neoplasms
• nosocomial infection
• pediatrics
• cancer care facilities
• antibiotics