PLoS ONE (Jan 2020)

Determinants of health-related quality of life among warfarin patients in Pakistan.

  • Muhammad Shahid Iqbal,
  • Fares M S Muthanna,
  • Yaman Walid Kassab,
  • Mohamed Azmi Hassali,
  • Fahad I Al-Saikhan,
  • Muhammad Zahid Iqbal,
  • Abdul Haseeb,
  • Muhammad Ahmed,
  • Salah-Ud-Din Khan,
  • Atta Abbas Naqvi,
  • Md Ashraful Islam,
  • Majid Ali

DOI
https://doi.org/10.1371/journal.pone.0234734
Journal volume & issue
Vol. 15, no. 6
p. e0234734

Abstract

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IntroductionThe effect of anticoagulation control on overall Health-Related Quality of Life (HRQoL) in patients taking warfarin in Pakistan has not been explored yet. Therefore, this study aimed to evaluate HRQoL among warfarin patients in Pakistan.MethodsThis cross-sectional study was conducted among patients on warfarin in Pakistan. By purposive sampling, data were collected using demographic data collection form and the World Health Organization Quality of Life: Brief Version (WHOQOL-BREF). The WHOQOL-BREF is comprised of four domains; physical, psychological, social relationships, and environment. Descriptive and inferential statistical analysis was done using SPSS version 22.ResultsOut of 295 warfarin patients, more females than males (ConclusionPatients had overall lower to moderate but satisfactory HRQoL scores in all four domains. Age, gender, employment status, education level, the indication of use and duration of warfarin therapy was associated with one or more domains of HRQoL among warfarin patients. The findings of this study would serve as a primary database for future studies. This study highlights how non-clinical factors could impact HRQoL in studied patients.