Cryptic insertion of MYC exons 2 and 3 into the immunoglobulin heavy chain locus detected by whole genome sequencing in a case of “MYC-negative” Burkitt lymphoma

• Rabea Wagener,
• Susanne Bens,
• Umut H. Toprak,
• Julian Seufert,
• Cristina López,
• Ingrid Scholz,
• Heidi Herbrueggen,
• Ilske Oschlies,
• Stephan Stilgenbauer,
• Matthias Schlesner,
• Wolfram Klapper,
• Birgit Burkhardt,
• Reiner Siebert

Affiliations

Rabea Wagener

Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm

Susanne Bens

Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm

Umut H. Toprak

German Cancer Research Center (DKFZ), Bioinformatics and Omics Data Analytics, Heidelberg;German Caner Research Center (DKFZ), Division of Neuroblastoma Genomics Heidelberg;Faculty of Biosciences, Heidelberg University, Heidelberg

Julian Seufert

German Cancer Research Center (DKFZ), Bioinformatics and Omics Data Analytics, Heidelberg;Faculty of Biosciences, Heidelberg University, Heidelberg

Cristina López

Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm

Ingrid Scholz

Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg

Heidi Herbrueggen

Department of Pediatric Hematology and Oncology, NHL-BFM Study Center, University Children’s Hospital, Münster

Ilske Oschlies

Hematopathology Section, Christian-Albrechts University, Kiel

Stephan Stilgenbauer

Department of Internal Medicine III, University of Ulm, Ulm, Germany

Matthias Schlesner

German Cancer Research Center (DKFZ), Bioinformatics and Omics Data Analytics, Heidelberg

Wolfram Klapper

Hematopathology Section, Christian-Albrechts University, Kiel

Birgit Burkhardt

Department of Pediatric Hematology and Oncology, NHL-BFM Study Center, University Children’s Hospital, Münster

Reiner Siebert

Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm