Quick determination of Glyphosate and AMPA at sub µg/L in drinking water by direct injection into LC-MS/MS

Abstract

A sensitive, simple and quick method for the determination of glyphosate (Gly) and its degradation product, Aminomethyl phosphonic acid (AMPA), in water through ion chromatography coupled to quadrupole-linear ion trap mass spectrometry has been developed. Sample treatment was based on direct injection and acquisition was implemented in both MS2 and MS3 modes. The LoQs of the method were 0.03 µ/L for both Gly-and AMPA. The recoveries were between 91 and 118% and RSD was lower than 15%. The developed methodology was applied on 436 water samples.

Keywords

• Glyphosate 1
• Water 2
• Liquid chromatography 3
• Mass spectrometry 4