Powerful decomposition of complex traits in a diploid model

Johan Hallin; Kaspar Märtens; Alexander I. Young; Martin Zackrisson; Francisco Salinas; Leopold Parts; Jonas Warringer; Gianni Liti

doi:10.1038/ncomms13311

Nature Communications (Nov 2016)

Powerful decomposition of complex traits in a diploid model

Johan Hallin,
Kaspar Märtens,
Alexander I. Young,
Martin Zackrisson,
Francisco Salinas,
Leopold Parts,
Jonas Warringer,
Gianni Liti

Affiliations

Johan Hallin: Institute for Research on Cancer and Aging, Nice (IRCAN), CNRS UMR7284, INSERM U1081, University of Nice Sophia Antipolis
Kaspar Märtens: Institute of Computer Science, University of Tartu
Alexander I. Young: Wellcome Trust Centre for Human Genetics, University of Oxford
Martin Zackrisson: Department of Chemistry and Molecular Biology, Gothenburg University
Francisco Salinas: Institute for Research on Cancer and Aging, Nice (IRCAN), CNRS UMR7284, INSERM U1081, University of Nice Sophia Antipolis
Leopold Parts: Institute of Computer Science, University of Tartu
Jonas Warringer: Department of Chemistry and Molecular Biology, Gothenburg University
Gianni Liti: Institute for Research on Cancer and Aging, Nice (IRCAN), CNRS UMR7284, INSERM U1081, University of Nice Sophia Antipolis

DOI: https://doi.org/10.1038/ncomms13311
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 9

Abstract

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Dissecting the architecture of complex trait is challenging. Here, Hallin, Märtens et al. devises Phased Outbred Lines (POLs) in order to accurately decompose growth trait variation in diploid yeast across different environments.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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