Chemical Profile and Biological Activities of Essential Oil from <i>Artemisia vulgaris</i> L. Cultivated in Brazil

Sonia Malik; Ludmilla  Santos Silva de Mesquita; Carolina  Rocha Silva; José  Wilson Carvalho de Mesquita; Emmeline de Sá Rocha; Jayakumar Bose; Rambod Abiri; Patricia de Maria Silva Figueiredo; Livio  M. Costa-Júnior

doi:10.3390/ph12020049

Pharmaceuticals (Apr 2019)

Chemical Profile and Biological Activities of Essential Oil from <i>Artemisia vulgaris</i> L. Cultivated in Brazil

Sonia Malik,
Ludmilla Santos Silva de Mesquita,
Carolina Rocha Silva,
José Wilson Carvalho de Mesquita,
Emmeline de Sá Rocha,
Jayakumar Bose,
Rambod Abiri,
Patricia de Maria Silva Figueiredo,
Livio M. Costa-Júnior

Affiliations

Sonia Malik: Graduate Program in Health Sciences, Biological and Health Sciences Center, Federal University of Maranhão, São Luís 65085-580, MA, Brazil
Ludmilla Santos Silva de Mesquita: Department of Pharmacy, Biological and Health Sciences Center, Federal University of Maranhão, São Luís 65085-580, MA, Brazil
Carolina Rocha Silva: Department of Pathology, Biological and Health Sciences Center, Federal University of Maranhão, São Luís 65085-580, MA, Brazil
José Wilson Carvalho de Mesquita: Department of Pharmacy, Biological and Health Sciences Center, Federal University of Maranhão, São Luís 65085-580, MA, Brazil
Emmeline de Sá Rocha: Department of Pharmacy, Biological and Health Sciences Center, Federal University of Maranhão, São Luís 65085-580, MA, Brazil
Jayakumar Bose: Australian Research Council Centre of Excellence in Plant Energy Biology, School of Agriculture, Food and Wine, Waite Research Institute, University of Adelaide, PMB 1, Glen Osmond, SA 5064, Australia
Rambod Abiri: Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, University Putra Malaysia, UPM Serdang 43400, Selangor DE, Malaysia
Patricia de Maria Silva Figueiredo: Department of Pharmacy, Biological and Health Sciences Center, Federal University of Maranhão, São Luís 65085-580, MA, Brazil
Livio M. Costa-Júnior: Department of Pathology, Biological and Health Sciences Center, Federal University of Maranhão, São Luís 65085-580, MA, Brazil

DOI: https://doi.org/10.3390/ph12020049
Journal volume & issue: Vol. 12, no. 2
p. 49

Abstract

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Essential oil from the leaves of Artemisia vulgaris L. (Compositae) cultivated in Brazil was investigated for its chemical composition and biological activities including antibacterial, antifungal, and anthelmintic. The constituents of essential oils isolated by hydro-distillation were examined by GC-MS and a total of 18 components were identified. The essential oil was dominated by oxygenated sesquiterpenes (44.4%), sesquiterpene hydrocarbons (33.3%), and oxygenated monoterpenes (16.6%). Caryophyllene (37.45%), germacrene D (16.17%), and humulene (13.66%) were the major components. The essential oils from A. vulgaris showed bactericidal and fungicidal properties against Staphylococcus aureus and Candida albicans, respectively. Anthelmintic activity against Haemonchus contortus was absent in this essential oil. Altogether above results indicate that essential oils from A. vulgaris can be used for various medicinal purposes.

Published in Pharmaceuticals

ISSN: 1424-8247 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine: Pharmacy and materia medica
Website: http://www.mdpi.com/journal/pharmaceuticals/

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