Nature Communications (Jun 2020)

Mutually stabilizing interactions between proto-peptides and RNA

  • Moran Frenkel-Pinter,
  • Jay W. Haynes,
  • Ahmad M. Mohyeldin,
  • Martin C,
  • Alyssa B. Sargon,
  • Anton S. Petrov,
  • Ramanarayanan Krishnamurthy,
  • Nicholas V. Hud,
  • Loren Dean Williams,
  • Luke J. Leman

DOI
https://doi.org/10.1038/s41467-020-16891-5
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 14

Abstract

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Cooperative relationships are widespread among different classes of biopolymers and are predicted to have existed during emergence of life. This study shows that proto-peptides engage in mutually stabilizing interactions with RNA, providing support for the co-evolution of these molecules.