Prediction of mortality at first admission in COVID-19 pneumonia: A retrospective cohort study

Abstract

The Coronovirus-19 (COVID-19) pandemic that started in Wuhan, China, at the end of 2019 may cause severe acute respiratory syndrome in some patients. We aimed to investigate the factors that can provide admission mortality prediction in patients with a definite diagnosis of COVID-19. We included patients with radiologically confirmed COVID-19 pneumonia with any significant comorbidities between February 2020-May 2020. We included 129 patients with a mean age of 58 ±15.3 years (range 16-88), 74 (57.4%) men, and of which 27 (21%) died in hospital. Age, aspartate aminotransferase (AST), gamma-glutamyltranspeptidase (GGT), albumin, international normalization ratio (INR), C-reactive protein (CRP), ferritin, d-dimer, and leukocyte levels differed between those who survived and died in the hospital. Multivariable regression showed increased odds of in-hospital death associated with older age (odds ratio 1.09 95% Confidence Interval [CI] (1.021-1.169; p=0.01), and ferritin 1.003 (1.001-1.004; p289 ng/mL had a 100% negative predictive value to differentiate surviving from in-hospital dead patients. [Med-Science 2022; 11(2.000): 457-61]

Keywords

• covid-19
• ferritin
• age
• mortality