Nature Communications (Apr 2020)

Natural killer cells modulate motor neuron-immune cell cross talk in models of Amyotrophic Lateral Sclerosis

  • Stefano Garofalo,
  • Germana Cocozza,
  • Alessandra Porzia,
  • Maurizio Inghilleri,
  • Marcello Raspa,
  • Ferdinando Scavizzi,
  • Eleonora Aronica,
  • Giovanni Bernardini,
  • Ling Peng,
  • Richard M. Ransohoff,
  • Angela Santoni,
  • Cristina Limatola

DOI
https://doi.org/10.1038/s41467-020-15644-8
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 16

Abstract

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Neuroimmune interactions are important in amyotrophic lateral sclerosis (ALS). Here the authors characterize the role of NK cells in mouse models of ALS, and in patient tissue.