Green Chemistry Letters and Reviews (Apr 2016)
Green and catalyst-free synthesis of olsalazine analogs
Abstract
A greener protocol for the synthesis of olsalazine analogs is reported. Olsalazine analogs are prepared in high yields by a one-pot reaction of two molecules of mesalazine with benzotriazole-activated aspartic acid and glutamic acid in water under microwave irradiation.
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