Factors associated with the risk of developing diabetes mellitus in patients with coronary artery disease

Abstract

Aim to determine the factors associated with the risk of developing type 2 diabetes in patients with coronary artery disease (CAD). Material and methods.The retrospective data sample included 181 patients hospitalized in the cardiology department of the SamSMU clinics. The patients were divided into two groups: group 1 122 patients without type 2 diabetes (77 (63.1%) men, median age 66.0 (59.0;75.0) years) and group 2 59 patients with type 2 diabetes (29 (49.2%) men, median age 69.0 (63.0;73.5) years). Results.The statistically significant difference (p0.05) was registered in glomerular filtration rate (GFR); no significant differences were demonstrated in other clinical indicators, including age and gender. Expectedly, the patients with type 2 diabetes had higher glucose levels. The parameters of the lipid spectrum and creatinine did not differ between the groups. Conclusion.The factors associated with the risk of developing type 2 diabetes are high glucose concentration and reduced GFR. The application of the developed discriminant analysis model will allow to determine the risk group of type 2 diabetes in patients with coronary heart disease, which will ensure a timely control of the presented indicators.

Keywords

• coronary artery disease
• type 2 diabetes mellitus
• risk factors
• glomerular filtration rate
• glucose concentration
• risk group