Importance and management of micronutrient deficiencies in patients with Alzheimer’s disease

Abstract

Bárbara Rita Cardoso,1 Cristiane Cominetti,2 Silvia Maria Franciscato Cozzolino11Faculty of Pharmaceutical Sciences, University of São Paulo (USP), São Paulo, Brazil; 2Faculty of Nutrition, Federal University of Goiás, Goiás, BrazilAbstract: Alzheimer’s disease (AD) is the most common form of dementia, and it generally affects the elderly. It has been suggested that diet is an intensively modifiable lifestyle factor that might reduce the risk of AD. Because epidemiological studies generally report the potential neuronal protective effects of various micronutrients, the aim of this study was to perform a literature review on the major nutrients that are related to AD, including selenium, vitamins C and E, transition metals, vitamin D, B-complex vitamins, and omega-3 fatty acids.Keywords: Alzheimer’s disease, nutritional deficiencies, diet, oxidative stress, lipid, vitamins

Keywords

• Alzheimer's disease
• nutritional deficiencies
• diet
• oxidative stress
• lipid
• vitamins.