Case Reports in Neurology (Apr 2018)

Autologous Bone Marrow Transplantation for Polymyositis Combined with Myasthenia Gravis and Aplastic Anemia: A Case Report

  • Sho Mitsumune,
  • Yasuhiro Manabe,
  • Taijun Yunoki,
  • Shyoichiro Kono,
  • Kazutoshi Aoyama,
  • Yoko Shinno,
  • Hisashi Narai,
  • Koji Abe

DOI
https://doi.org/10.1159/000488476
Journal volume & issue
Vol. 10, no. 1
pp. 108 – 111

Abstract

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This is the first report about a patient with concomitant polymyositis (PM), myasthenia gravis (MG), and aplastic anemia (AA). A 54-year-old male developed myalgia and muscle weakness, which gradually progressed over 2 months. He was persistently affected by MG and AA. Brachium magnetic resonance imaging showed increased signal intensity in the left triceps and deltoid muscles on short tau inversion recovery images. A muscle biopsy examination revealed perifascicular atrophication and inflammatory myopathy. We diagnosed the patient with PM combined with MG and AA. He was successfully treated with an autologous bone marrow transplantation (BMT). The present case suggests that BMT is a therapeutic option for PM, MG, and AA.

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