Design, Characterization, and 3D Printing of Cardiovascular Stents with Zero Poisson’s Ratio in Longitudinal Deformation

Chengjin Wang; Lei Zhang; Yongcong Fang; Wei Sun

Engineering (Jul 2021)

Design, Characterization, and 3D Printing of Cardiovascular Stents with Zero Poisson’s Ratio in Longitudinal Deformation

Chengjin Wang,
Lei Zhang,
Yongcong Fang,
Wei Sun

Affiliations

Chengjin Wang: Biomanufacturing Center, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China; Biomanufacturing and Rapid Forming Technology Key Laboratory of Beijing, Beijing 100084, China; “Biomanufacturing and Engineering Living Systems” Innovation International Talents Base (111 Base), Beijing 100084, China
Lei Zhang: Biomanufacturing Center, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China; Biomanufacturing and Rapid Forming Technology Key Laboratory of Beijing, Beijing 100084, China; “Biomanufacturing and Engineering Living Systems” Innovation International Talents Base (111 Base), Beijing 100084, China; Corresponding author.
Yongcong Fang: Biomanufacturing Center, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China; Biomanufacturing and Rapid Forming Technology Key Laboratory of Beijing, Beijing 100084, China; “Biomanufacturing and Engineering Living Systems” Innovation International Talents Base (111 Base), Beijing 100084, China
Wei Sun: Biomanufacturing Center, Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China; Biomanufacturing and Rapid Forming Technology Key Laboratory of Beijing, Beijing 100084, China; “Biomanufacturing and Engineering Living Systems” Innovation International Talents Base (111 Base), Beijing 100084, China; Department of Mechanical Engineering, Drexel University, Philadelphia, PA 19104, USA

Journal volume & issue: Vol. 7, no. 7
pp. 979 – 990

Abstract

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Inherent drawbacks associated with drug-eluting stents have prompted the development of bioresorbable cardiovascular stents. Additive manufacturing (3-dimentional (3D) printing) has been widely applied in medical devices. In this study, we develop a novel screw extrusion-based 3D printing system with a new designed mini-screw extruder to fabricate stents. A stent with a zero Poisson’s ratio (ZPR) structure is designed, and a preliminary monofilament test is conducted to investigate appropriate fabrication parameters. 3D-printed stents with different geometric structures are fabricated and analyzed by observation of the surface morphology. An evaluation of the mechanical properties and a preliminary biological evaluation of 3D-printed stents with different parameters are carried out. In conclusion, the screw extrusion-based 3D printing system shows potential for customizable stent fabrication.

Published in Engineering

ISSN: 2095-8099 (Print); 2096-0026 (Online)
Publisher: Elsevier
Country of publisher: China
LCC subjects: Technology: Engineering (General). Civil engineering (General)
Website: http://www.journals.elsevier.com/engineering

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