FIVE REASONS TO PRESCRIBE A MACROLIDE FOR ENT DISEASE

Abstract

Macrolides are antibiotics the chemical structure of which has a macrocyclic lactone ring. Macrolides have several advantages over other groups of antibiotics. They are characterized by high antibacterial activity against intracellular pathogens and have anti-inflammatory, immunomodulatory effects and regulate the mucus. The article names five reasons to prescribe macrolides for diseases of the upper respiratory tract: cross sensitivity to penicillin antibiotics; combination of inflammatory disease of the upper respiratory tract and ear with allergic disease; infections caused by atypical microorganisms (chlamydia, mycoplasma, etc.); upper respiratory tract infection characterized by biofilm formation; chronic rhinosinusitis with or without polyps, withpersistent course, frequent relapses and low efficiency of surgical treatment.

Keywords

• macrolides
• azithromycin
• azitral
• diseases of the upper respiratory tract