Assessment of the cardiorespiratory state in a six-minute walk test in patients with chronic obstructive pulmonary disease with normal body mass and overweight

Abstract

Chronic obstructive pulmonary disease (COPD) and overweight/obesity are among the leading health problems worldwide.The objective: to conduct a comparative analysis of exercise tolerance in patients with COPD with normal body mass and overweight during a six-minute walk test using an original device for cardiorespiratory analysis and a method for assessing cardiorespiratory status.Subjects and methods. 192 COPD patients were enrolled in the study. Patients were divided into two groups - with normal body mass and overweight. To assess exercise tolerance, six-minute walk test was used simultaneously with the device we developed specifically for cardiorespiratory analysis. The distance covered within 6 min (6MWD) was compared with the proper indicator of 6MWD (i).Results. In patients with normal body weight compared with patients with overweight, the following indicators were significantly lower: the average ratio of 6MWD/6MWD (i) (p = 0.0121), the level of oxygen saturation after 6-minute walking test, % of fat, and % of muscle. A direct correlation was observed between 6MWD and BMI (r = 0.54, p = 0.002), and between 6MWD and % of muscles (r = 0.58, p = 0.012).Conclusion. Overweight patients with COPD have a higher exercise tolerance compared with patients with normal body weight, which can be partly explained by differences in the body composition with a significantly lower percentage of muscle mass in patients with normal body weight.

Keywords

• хроническая обструктивная болезнь легких
• избыточная масса тела
• устройство кардиореспираторного анализа
• тест шестиминутной ходьбы