CHIMIA (May 2010)
Recent Biomimetic and Organocatalytic Syntheses of ?-Tocopherol
Abstract
We report here on our efforts to develop new strategies for the synthesis of ?-tocopherol, the biologically most significant member of the vitamin E family. This review comprises five new methods to generate the chiral chromane of ?-tocopherol with overall up to 29% yield from commercially available material and up to 94% de.
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