Наукові горизонти (Jan 2020)

THE MORPHOLOGY OF THE HARDERIAN GLAND CHICKEN’S FOR VACCINATION AND APPLICATION OF AVESSTIMTM

  • S. Guralska ,
  • T. Budnik

DOI
https://doi.org/10.33249/2663-2144-2020-86-1-79-88
Journal volume & issue
Vol. 86, no. 1
pp. 79 – 88

Abstract

Read online

Usіng immunomodulators in veterinary medicine is a perspective direction for the stimulation of non-specific and specific resistance, the creation of antiviral effects, and also for increase the preservation and productivity of agricultural bird. The purpose of the work was research the effect preparation Avestimtm to microscopic structure and morphometric indicators of garderian glands of chickens for vaccination of infectious bronchitis. In work we use anatomical, histological, morphometrical, statistical. The results indicate that using immunomodulator Avesstimtm of the vaccinated chickens affects the development of the organ, the increase of the total area of lymphoid formation, which demonstrates the expediency of use this immunomodulator. Analysis of research show that the absolute mass of the gland of 8 and 20-daily vaccinated chickens, which was added immunomodulator, probably increased in 1.27 (P<0.01) and 1.14 (P<0.05) times compared to only vaccinated chickens. Results of morphometric research showed that the area of secretory lobules and lymphoid formations is much more in the gland chickens of 40, 90 and 110-daily age, which added to the main diet preparation the Avesstimtm. So, the 40-daily chickens age of the experienced group has been the growth of the area of lymphoid formations: in 1.1 by times compared to only vaccinated, and in 1.26 by times (P<0.01) in compared with the controls. And, the size of the organ significantly correlates with development of lymphoid formations because the area of lobules secretarial department of chickens gland in research groups is no different from the control group's indicators. At that, in an experimental group of 110-daily chickens age took place increased lymphoid tissue and detect areas of permeation into the secretory part of the gland. So, character of morfological, histological and morphometrical changes in garderian gland of the chickens vaccinated against of infectious bronchitis and using immunomodulator Avesstimtm most pronounced of chickens 40, 90-daily age. Usіng immunomodulator Avesstimtm during vaccination stimulate formation lymphoid nodules in garderian gland of chickens 40, 90-daily age.

Keywords