Journal of Cardiovascular Emergencies (Dec 2016)

Detection of Myocardial Injury Using miRNAs Expression as Genetic Biomarkers in Acute Cardiac Care

  • Rogobete Alexandru Florin,
  • Bedreag Ovidiu Horea,
  • Popovici Sonia Elena,
  • Sas Adriana Mariana,
  • Stan Adrian Tudor,
  • Stoicescu Emil Robert,
  • Sandesc Dorel

DOI
https://doi.org/10.1515/jce-2016-0025
Journal volume & issue
Vol. 2, no. 4
pp. 169 – 172

Abstract

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Cardiovascular disease is a leading cause of death globally. At present, there are many ways to diagnose this pathophysiology. The greatest disadvantages related to current biomarkers are their low specificity, low selectivity and low accuracy. A new method, extensively studied recently, is the expression of miRNAs, used as genetic biomarkers for the early diagnosis of cardiovascular diseases. This paper presents an update of miRNAs species expression that can serve as early diagnostic biomarkers and for the continuous monitoring of patients with cardiovascular disease.

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