Nature Communications (Mar 2019)

Waveguide-PAINT offers an open platform for large field-of-view super-resolution imaging

  • Anna Archetti,
  • Evgenii Glushkov,
  • Christian Sieben,
  • Anton Stroganov,
  • Aleksandra Radenovic,
  • Suliana Manley

DOI
https://doi.org/10.1038/s41467-019-09247-1
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 9

Abstract

Read online

TIRF imaging is limited by the size and uniformity of the illumination. Here the authors present a waveguide solution to create a large area of uniform evanescent illumination suitable for single molecule imaging coupled with a customised sample holder containing a reservoir for DNA-PAINT solutions.