Nature Communications (Jun 2021)

Saturated free fatty acids and association with memory formation

  • Tristan P. Wallis,
  • Bharat G. Venkatesh,
  • Vinod K. Narayana,
  • David Kvaskoff,
  • Alan Ho,
  • Robert K. Sullivan,
  • François Windels,
  • Pankaj Sah,
  • Frédéric A. Meunier

DOI
https://doi.org/10.1038/s41467-021-23840-3
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 11

Abstract

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Changes in poly-unsaturated free fatty acids (FFAs) have been associated with LTP. Here, using lipidomics analysis the authors characterise FFA changes in the rat brain associated with fear conditioning, and demonstrate that increases in saturated FFAs represent the major change.