Journal of Clinical Medicine (Feb 2022)

Post-SARS-CoV-2 Acute Telogen Effluvium: An Expected Complication

  • Paola Monari,
  • Giulio Gualdi,
  • Giorgio Bettoni,
  • Raffaella Costa,
  • Giorgio Ragni,
  • Francesca Zani,
  • Giovanna Bianchi,
  • Silvia Casella,
  • Elisa Casella,
  • Massimo Crippa,
  • Piergiacomo Calzavara Pinton,
  • Marta Di Nicola,
  • Annamaria Porreca,
  • Paolo Amerio,
  • Pierangelo Guizzi

DOI
https://doi.org/10.3390/jcm11051234
Journal volume & issue
Vol. 11, no. 5
p. 1234

Abstract

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Post-SARS-CoV-2 telogen effluvium has been described in case reports of COVID-19 patients. We evaluated the prevalence of post-SARS-CoV-2 telogen effluvium in patients from a single medical center, exploring any causal links with the infection. Our hospital-based, cross-sectional study was conducted with patient participants discharged with a diagnosis of SARS-CoV-2 pneumonia from 1 March to 4 April 2020. All patients were evaluated by the same senior dermatologist; a clinical/dermatoscopic evaluation was performed. Alopecia was assessed in 31.3% of patients, with a significant difference in sex (females 73%, males 26.7%). The average time detected from the onset of the first symptoms to alopecia was 68.43 days. Overall, there were no significant associations between alopecia and COVID-19-related features (length of hospitalization, virologic positivity, or duration of fever), treatment characteristics, or laboratory findings. In this paper, we report that post-infection acute telogen effluvium occurs in a significant number of COVID-19 patients. The burden of this condition may impair the quality of life, with a significant impact on individuals.

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