mBio (Jun 2021)

Circadian Clock Control of Translation Initiation Factor eIF2α Activity Requires eIF2γ-Dependent Recruitment of Rhythmic PPP-1 Phosphatase in <i>Neurospora crassa</i>

  • Zhaolan Ding,
  • Teresa M. Lamb,
  • Ahmad Boukhris,
  • Rachel Porter,
  • Deborah Bell-Pedersen

DOI
https://doi.org/10.1128/mBio.00871-21
Journal volume & issue
Vol. 12, no. 3

Abstract

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Circadian clock control of mRNA translation contributes to the daily cycling of a significant proportion of the cellular protein synthesis, but how this is accomplished is not understood. We discovered that the clock in the model fungus Neurospora crassa