Address for correspondence: Dr. Jean-Luc Balligand, FATH/IREC, Tour Laënnec +3, B1.57.04, 57 avenue Hippocrate, 1200 Brussels, Belgium.; Pole of Pharmacology and Therapeutics (FATH), Institute for Clinical and Experimental Research (IREC), UCLouvain and Cliniques Universitaires Saint-Luc, Brussels, Belgium