Thymodepressin—Unforeseen Immunosuppressor

Abstract

The paper summarizes the available information concerning the biological properties and biomedical applications of Thymodepressin. This synthetic peptide drug displays pronounced immunoinhibitory activity across a wide range of conditions in vitro and in vivo. The history of its unforeseen discovery is briefly reviewed, and the current as well as potential expansion areas of medicinal practice are outlined. Additional experimental evidence is obtained, demonstrating several potential advantages of Thymodepressin over another actively used immunosuppressor drug, cyclosporin A.

Keywords

• new peptide immunosuppressor
• reciprocal activity peptide enantiomers
• autoimmune treatment
• comparison with cyclosporine A