Sensitivity and Specificity of CardioChek®PA in Detecting Individuals with Abnormal Cholesterol and Glucose Level

Abstract

Point of care screening to identify individuals with abnormal blood lipid and glucose is recommended eligible individuals for primary prevention of cardiovascular disease. The study was done among 252 clients to determine the ability of CardioChek®PA in identifying individuals with abnormal blood levels of total cholesterol (TC) and Blood Glucose (BG), compared with a reference laboratory. Pearson correlation coefficients between reference laboratory and fingerstick test were fair to moderate and were statistically significant (p<0.05). Categorical agreement between fingerstick analysis and the reference laboratory was fair to moderate for TC and BG respectively. For TC, CardioChek®PA had 62.7% sensitivity, 76.1% specificity, and 76.4% Positive Predictive Value. For glucose, CardioChek®PA had 95.5% sensitivity, 85.4% specificity and 70.3% Positive Predictive Value. In conclusion, CardioChek®PA is a reliable tool to be used as screening tool for identification of individuals at risk for cardiovascular disease.

Keywords

• CardioChek®PA
• screening
• sensitivity
• specificity
• Malaysia.