Kefir protects the liver against high fructose corn syrup induced phosphodiesterase hyperactivity

Abstract

Phosphodiesterases (PDEs) mediate several physiological activities, and alterations in PDE expressions might cause conflicts between functional and clinical effects. This study clarifies the eventual relationship between the hepatic insulin resistance-associated signaling elements and PDEs together with inflammatory markers and investigates the role of kefir in the treatment.

Keywords

• hfcs
• inflammation
• insulin signaling pathway
• kefir
• phosphodiesterase
• yfms
• kefir
• fosfodiesteraz
• insülin sinyal yolu
• inflamasyon