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Disease Models & Mechanisms
(Oct 2023)
Efficient genetic editing of human intestinal organoids using ribonucleoprotein-based CRISPR
Nefeli Skoufou-Papoutsaki,
Sam Adler,
Paula D'Santos,
Liz Mannion,
Shenay Mehmed,
Richard Kemp,
Amy Smith,
Francesca Perrone,
Komal Nayak,
Alasdair Russell,
Matthias Zilbauer,
Douglas J. Winton
Affiliations
Nefeli Skoufou-Papoutsaki
CRUK Cambridge Institute, Cambridge CB2 0RE, UK
Sam Adler
CRUK Cambridge Institute, Cambridge CB2 0RE, UK
Paula D'Santos
CRUK Cambridge Institute, Cambridge CB2 0RE, UK
Liz Mannion
CRUK Cambridge Institute, Cambridge CB2 0RE, UK
Shenay Mehmed
CRUK Cambridge Institute, Cambridge CB2 0RE, UK
Richard Kemp
CRUK Cambridge Institute, Cambridge CB2 0RE, UK
Amy Smith
CRUK Cambridge Institute, Cambridge CB2 0RE, UK
Francesca Perrone
Wellcome-MRC Cambridge Stem Cell Institute, Cambridge CB2 0RE, UK
Komal Nayak
Wellcome-MRC Cambridge Stem Cell Institute, Cambridge CB2 0RE, UK
Alasdair Russell
CRUK Cambridge Institute, Cambridge CB2 0RE, UK
Matthias Zilbauer
Wellcome-MRC Cambridge Stem Cell Institute, Cambridge CB2 0RE, UK
Douglas J. Winton
CRUK Cambridge Institute, Cambridge CB2 0RE, UK
DOI
https://doi.org/10.1242/dmm.050279
Journal volume & issue
Vol. 16, no. 10
Abstract
Read online
No abstracts available.
Keywords
pten
genome editing
organoids
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