Methyl 4-(4-chlorophenyl)-8-iodo-2-methyl-6-oxo-1,6-dihydro-4H-pyrimido[2,1-b]quinazoline-3-carboxylate

Abstract

In the title compound, C20H15ClIN3O3, the dihedral angle between the quinazolinone ring system [r.m.s. deviation = 0.047 (2) Å] and the pendant benzene ring is 82.63 (11)°. The molecular conformation is stabilized by intramolecular C—H...O interactions. In the crystal, the molecules are linked by N—H...O hydrogen bonds into chains along the a-axis direction. Another set of chains propagating along [101] is formed due to intermolecular I...Cl short contacts of 3.427 (1) Å, thus giving layers parallel to (010). The layers are connected by C—H...π and π–π interactions, the shortest distance between the centroids of aromatic rings being 3.8143 (16) Å.