Langerhans' cell histiocytosis of the temporal bone in an adult with central diabetes insipidus

Abstract

We present a case of Langerhans’ cell histiocytosis in a 40-year-old woman presenting with central diabetes insipidus and right ear pain. As this disease process is often clinically challenging, the presence of certain imaging findings should raise the possibility of this diagnosis. We review the pertinent imaging and correlate with histology and immunohistochemistry leading to the diagnosis. Keywords: Langerhans cell histiocytosis, Adult, Histology, CT temporal bone, MRI