مجلة كلية الطب (Jan 2007)

Possible Role for Interleukin-5 in Asthma

  • Yacoob Y. Al-Rubaeyi,
  • Batool A. Al-Haidary,
  • Wala'a E. Jasim

Journal volume & issue
Vol. 48, no. 4

Abstract

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Background: Asthma is an allergic disease characterized by airway obstruction as a result of cellular accumulation due to the liberation of certain mediators. Among those mediators are the cytokines such as IL-5. Patients & Methods: Interleukin-5 concentration has been estimated in 94 sera samples of Asthmatic patients in comparison with 41 non-asthmatic bronchitis as patient controls in addition to 30 apparent healthy control group using ELISA method. Results & Conclusions: There is highly significant elevation of IL-5 in the asthmatic cases in comparison with healthy controls (P< 0.001). We conclude that this cytokine may play the major role in asthmatic attack & it may be a good marker for the disease.

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