Discovery of novel non-peptidic and non-covalent small-molecule 3CLpro inhibitors as potential candidate for COVID-19 treatment

• Zhidong Jiang,
• Bo Feng,
• Yumin Zhang,
• Tianqing Nie,
• Hong Liu,
• Jia Li,
• Haixia Su,
• Leike Zhang,
• Yi Zang,
• Yu Zhou

Affiliations

Zhidong Jiang

School of Life Science and Technology, ShanghaiTech University

Bo Feng

Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Yumin Zhang

State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences

Tianqing Nie

Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Hong Liu

Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Jia Li

Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Haixia Su

Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Leike Zhang

State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences

Yi Zang

School of Life Science and Technology, ShanghaiTech University

Yu Zhou

School of Life Science and Technology, ShanghaiTech University