Family loading and morbidity risk of attention-deficit hyperactivity disorder in patients with alcohol-dependence syndrome

Abstract

Background: Attention-deficit hyperactivity disorder (ADHD) and substance-use disorders often co-occur. Aim: Aim of this study was to look at the family loading of ADHD (in adults and children) in patients with alcohol-dependence syndrome (ADS) along with the estimation of morbidity risk (MR) for developing ADHD. Methods: Thirty-five male patients with ADS along with their 369 first-degree relatives (FDRs) – both children and adults – were recruited. Results: ADHD and residual ADD (ADDRT) were significantly more common in the early-onset (EO) ADS group and their FDR. In ADHD children, high MR (27.27%) for developing EO of ADS was noted. Discussion: Findings from this study raise an avenue for research in the Indian population about the shared risk between ADS and ADHD.

Keywords

• Attention-deficit hyperactivity disorder
• alcohol-dependence syndrome
• family loading
• morbidity risk