Терапевтический архив (Sep 2020)

The eosinophilic esophagitis and IgG4-related disease involving the esophagus

  • N. V. Bakulina,
  • V. I. Simanenkov,
  • S. L. Vorobyev,
  • S. V. Tikhonov,
  • N. B. Lishchuk,
  • I. G. Bakulin

DOI
https://doi.org/10.26442/00403660.2020.08.000792
Journal volume & issue
Vol. 92, no. 8
pp. 100 – 107

Abstract

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The study of eosinophilic esophagitis has become a dynamic field with an evolving understanding of the pathogenesis, diagnosis, and treatment. Immunoglobulin G4 (IgG4)-related disease exhibits systemic involvement but very rarely involves the esophagus. The article presents a clinical case: the history of ulcer and stricture of the esophagus in a young man of 17 years. The patient was finally diagnosed with IgG4-related and eosinophilic esophagitis and showed a good response to corticosteroid therapy. We herein report a rare case of dysphagia associated with IgG4-related disease and eosinophilic. We presented a review of modern data on the relationship of eosinophilic esophagitis and pathological IgG4-response.

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