Сеченовский вестник (Dec 2022)

A possible interconnection between the sensitivity to phenyltiokarbimid and alcohol dependence

  • O. V. Myachina,
  • A. A. Zuykova,
  • A. N. Pashkov,
  • S. N. Popov

Journal volume & issue
Vol. 0, no. 1-2
pp. 30 – 34

Abstract

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The aim of this research is to investigate the connection between sensitivity to phenyltiokarbimid (PHTK) and alcohol dependence. The determination of the sensitivity to PHTK is based on those methodes named after H. Harris and H. Kalmus (1949). The distribution of PHTK sensitivity is studied on the amount of 91 patients: 59 of them are with the diagnosis «moderate nonalcoholic syndrome», 33 of them are with the diagnosis «the syndrome of alcohol and delirium cancellation». The group of patients under consideration consisted of 29 healthy men. Statistically significant lowering of the threshold of taste sensitivity to PHTK is revealed. The conclusion is that a significant amount of non-sensitive patients who are alcohol dependent are found.

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