Isotype-Specific Fc Effector Functions Enhance Antibody-Mediated Rift Valley Fever Virus Protection
<i>In Vivo</i>

Haley N. Cartwright; Dominique J. Barbeau; Anita K. McElroy

doi:10.1128/mSphere.00556-21

mSphere (Oct 2021)

Isotype-Specific Fc Effector Functions Enhance Antibody-Mediated Rift Valley Fever Virus Protection <i>In Vivo</i>

Haley N. Cartwright,
Dominique J. Barbeau,
Anita K. McElroy

Affiliations

Haley N. Cartwright: ORCiD; University of Pittsburgh, School of Medicine, Department of Pediatrics, Division of Pediatric Infectious Disease, and Center for Vaccine Research, Pittsburgh, Pennsylvania, USA
Dominique J. Barbeau: ORCiD; University of Pittsburgh, School of Medicine, Department of Pediatrics, Division of Pediatric Infectious Disease, and Center for Vaccine Research, Pittsburgh, Pennsylvania, USA
Anita K. McElroy: ORCiD; University of Pittsburgh, School of Medicine, Department of Pediatrics, Division of Pediatric Infectious Disease, and Center for Vaccine Research, Pittsburgh, Pennsylvania, USA

DOI: https://doi.org/10.1128/mSphere.00556-21
Journal volume & issue: Vol. 6, no. 5

Abstract

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Rift Valley fever virus (RVFV) is a mosquito-borne virus found throughout Africa and into the Middle East. It has a substantial disease burden; in areas of endemicity, up to 60% of adults are seropositive.

Published in mSphere

ISSN: 2379-5042 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/msphere

About the journal