Acute Medicine & Surgery (Jan 2023)

Successfully treated case of severe hypothermia secondary to myxedema coma

  • Hirotsugu Yamamoto,
  • Takashi Hongo,
  • Tsuyoshi Nojima,
  • Takafumi Obara,
  • Yoshinori Kosaki,
  • Kohei Ageta,
  • Kohei Tsukahara,
  • Tetsuya Yumoto,
  • Atsunori Nakao,
  • Hiromichi Naito

DOI
https://doi.org/10.1002/ams2.828
Journal volume & issue
Vol. 10, no. 1
pp. n/a – n/a

Abstract

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Background Myxedema coma is an extremely rare but fatal endocrine emergency that requires urgent recognition and treatment. We describe a case of severe hypothermia that rapidly deteriorated to cardiac arrest that was attributed to myxedema coma. Case Presentation A 52‐year‐old man without a history of hypothyroidism was transferred to our emergency department due to coma and profound hypothermia. The patient developed cardiac arrest immediately after hospital arrival but return of spontaneous circulation was achieved shortly after resuscitation. The patient was noted to have generalized, nonpitting edema, dry skin, severe respiratory acidosis, hyponatremia, and elevated creatinine kinase, which was indicative of hypothyroidism. Myxedema coma was confirmed by a thyroid profile. The patient was successfully treated with intravenous levothyroxine and glucocorticoid. Conclusion Although myxedema coma is a rare cause of severe hypothermia, emergency physicians should be familiar with its clinical features and management.

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