OXYGEN TRANSPORT FUNCTION AND GAS TRANSMITTERS OF THE BLOOD DURING CHRONIC ATHEROSCLEROTIC OCCLUSION OF THE SUPERFICIAL FEMORAL ARTERY AND AFTER LOOP ENDATERECTOMY

Abstract

Background. The restoration of arterial blood flow does not guarantee the restoration of adequate oxygenation of the tissues of the lower extremity after chronic ischemia.Purpose. To study the patterns of changes in oxygen transport function (OTF) and blood gas transmitters in patients who underwent loop endaterectomy (LEAE) from the superficial femoral artery (SFA).Material and methods. We examined 103 patients with occlusion of SFA, which was eliminated by the method of LEAE. The OTF indices, the content of nitrogen monoxide and hydrogen sulfide were determined before the operation as well as on the third and eighth day of the postoperative period.Results. The obtained data suggested an increase in the saturation of venous blood with oxygen and concentration of gas transmitters in сhronic ischemia and after LEAE.Conclusions. The revealed patterns substantiate the effectiveness of LEAE for chronic lower limb ischemia.

Keywords

• ischemia-reperfusion
• revascularization
• oxygen transport function
• endaterectomy
• gas transmitters