The ins and outs of extracellular vesicles

Abstract

Extracellular vesicles refer a population of vesicles bodies including ectosomes, apoptosis bodies, oncosomes and exosomes released by cells. And as an important intercellular signaling tool, they play vital roles in various pathological processes. In recent years, the research focusing on extracellular vesicles has developed rapidly, and the basic research and the transformational application research have been going hand in hand.Extracellular vesicles can not only be used as an important target for liquid biopsies, but also provide a promising idea for drug delivery. This paper will review the formation, physiological and pathological function, purification and detection methods and transformational research progress of extracellular vesicles. We look forward to the transformation of extracellular vesicles into clinical applications as soon as possible, and bringing good news to patients.

Keywords

• extracellular vesicles
• exosome
• liquid biopsy
• drug delivery