Sensitizing Properties of Antigen Preparations Obtained from Brucella in S- and L-Forms

Abstract

It is known that S-form Brucella causes allergic transformation in a macroorganism, which is manifested as delayed-type hypersensitivity reaction. This capacity in atypical variants (L-forms) is under-investigated. It is demonstrated that corpuscular antigen in B. abortus 19BA vaccine and thermoextract prepared from B. abortus I-206 in S-form when threefold administered cause marked sensibilization; while corpuscular antigen and thermoextract produced from Brucella in L-form, and thermoextract from Brucella in S-form in case of one time administration do not have such an effect on leucocytes of white mice.

Keywords

• бруцеллы
• s- и l-форма
• термоэкстракт
• сенсибилизация лейкоцитов
• коэффициент лейкоцитолиза
• brucella
• s- and l-forms
• thermoextract
• leukocyte sensibilization
• leukocytolysis index