Integrative Cancer Therapies (Jun 2017)
Interest in Integrative Medicine Among Postmenopausal Hormone Receptor–Positive Breast Cancer Patients in the EvAluate-TM Study
- Carolin C. Hack MD,
- Peter A. Fasching MD,
- Tanja Fehm MD,
- Johann de Waal MD,
- Mahdi Rezai MD,
- Bernd Baier MD,
- Gerold Baake MD,
- Hans-Christian Kolberg MD,
- Martin Guggenberger MD,
- Mathias Warm MD,
- Nadia Harbeck MD,
- Rachel Wuerstlein MD,
- Jörg-Uwe Deuker MD,
- Peter Dall MD,
- Barbara Richter MD,
- Grischa Wachsmann MD,
- Cosima Brucker MD,
- Jan W. Siebers MD,
- Nikos Fersis MD,
- Thomas Kuhn MD,
- Christopher Wolf MD,
- Hans-Walter Vollert MD,
- Georg-Peter Breitbach MD,
- Wolfgang Janni MD,
- Robert Landthaler MD,
- Andreas Kohls MD,
- Daniela Rezek MD,
- Thomas Noesslet MD,
- Gunnar Fischer MD,
- Stefan Henschen MD,
- Thomas Praetz MD,
- Volker Heyl MD,
- Thorsten Kühn MD,
- Thomas Krauss MD,
- Christoph Thomssen MD,
- Andre Hohn MD,
- Hans Tesch MD,
- Christoph Mundhenke MD,
- Alexander Hein MD,
- Claudia Rauh MD,
- Christian M. Bayer MD,
- Adib Jacob,
- Katja Schmidt PhD,
- Erik Belleville PhD,
- Peyman Hadji MD,
- Sara Y. Brucker MD,
- Diethelm Wallwiener MD,
- Sherko Kümmel MD,
- Matthias W. Beckmann MD,
- Daniela Paepke MD
Affiliations
- Carolin C. Hack MD
- Universitäts-Brustzentrum Franken, Frauenklinik, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen–European Metropolitan area Nuremberg (CCC ER-EMN), Germany
- Peter A. Fasching MD
- Universitäts-Brustzentrum Franken, Frauenklinik, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen–European Metropolitan area Nuremberg (CCC ER-EMN), Germany
- Tanja Fehm MD
- Department für Frauengesundheit, Universitätsklinikum Tübingen, Eberhard-Karls-Universität, Tübingen, Germany
- Johann de Waal MD
- Frauenklinik im Klinikum Dachau, Dachau, Germany
- Mahdi Rezai MD
- Luisenkrankenhaus Düsseldorf, Düsseldorf, Germany
- Bernd Baier MD
- Frauenklinik im Klinikum Dachau, Dachau, Germany
- Gerold Baake MD
- Onkologische Praxis Pinneberg, Pinneberg, Germany
- Hans-Christian Kolberg MD
- Marienhospital Bottrop, Bottrop, Germany
- Martin Guggenberger MD
- Klinikum Tuttlingen, Germany
- Mathias Warm MD
- Brustzentrum, Klinken der Stadt Cologne gGmbH, Holweide, Germany
- Nadia Harbeck MD
- Brustzentrum der Universität München, Frauenkliniken Grosshadern und Maistrasse, Munich, Germany
- Rachel Wuerstlein MD
- Brustzentrum der Universität München, Frauenkliniken Grosshadern und Maistrasse, Munich, Germany
- Jörg-Uwe Deuker MD
- Vinzenzkrankenhaus Hanover gGmbH, Hanover, Germany
- Peter Dall MD
- Frauenklinik, Städtisches Klinikum Lüneburg, Lüneburg, Germany
- Barbara Richter MD
- Elblandkliniken Meissen-Radebeul, Radebeul, Germany
- Grischa Wachsmann MD
- Kreiskrankenhaus Böblingen, Böblingen, Germany
- Cosima Brucker MD
- Universitätsklinik für Frauenheilkunde, Paracelsus Medizinische Privatuniversität, Nuremberg, Germany
- Jan W. Siebers MD
- Frauenklinik der St. Josefsklinik, Offenburg, Germany
- Nikos Fersis MD
- Frauenklinik, Klinikum Bayreuth GmbH, CCC ER-EMN, Bayreuth, Germany
- Thomas Kuhn MD
- Karl-Olga-Krankenhaus, Stuttgart, Germany
- Christopher Wolf MD
- Medizinisches Zentrum Ulm, Ulm, Germany
- Hans-Walter Vollert MD
- Klinikum Friedrichshafen, Friedrichshafen, Germany
- Georg-Peter Breitbach MD
- Städtisches Klinikum Neunkirchen Gynäkologie und Geburtshilfe, Neunkirchen, Germany
- Wolfgang Janni MD
- Frauenklinik des Universitätsklinikums Ulm, Ulm, Germany
- Robert Landthaler MD
- Gynäkologische Praxis in der Kreisklinik Krumbach, Krumbach, Germany
- Andreas Kohls MD
- Evangelisches Krankenhaus Ludwigsfelde-Teltow, Ludwigsfelde, Germany
- Daniela Rezek MD
- Marien-Hospital Wesel, Wesel, Germany
- Thomas Noesslet MD
- Frauenklinik am Kreiskrankenhaus Hameln, Hameln, Germany
- Gunnar Fischer MD
- Landkreis Mittweida Krankenhaus gGmbH, Mittweida, Germany
- Stefan Henschen MD
- Johanniter Krankenhaus Genthin Stendal gGmbH, Stendal, Germany
- Thomas Praetz MD
- Caritas-Krankenhaus, Bad Mergentheim, Germany
- Volker Heyl MD
- Asklepios Paulinen Klinik, Wiesbaden, Germany
- Thorsten Kühn MD
- Frauenklinik, Städtische Kliniken, Esslingen am Neckar, Germany
- Thomas Krauss MD
- Frauenklinik Lippe-Detmold, Detmold, Germany
- Christoph Thomssen MD
- Frauenklinik, Martin Luther University, Halle-Wittenberg, Germany
- Andre Hohn MD
- Kreiskrankenhaus Rendsburg, Rendsburg, Germany
- Hans Tesch MD
- Onkologie Bethanien Frankfurt, Frankfurt, Germany
- Christoph Mundhenke MD
- Frauenklinik, Universitätsklinikum Schleswig-Holstein Campus Kiel, Kiel, Germany
- Alexander Hein MD
- Universitäts-Brustzentrum Franken, Frauenklinik, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen–European Metropolitan area Nuremberg (CCC ER-EMN), Germany
- Claudia Rauh MD
- Universitäts-Brustzentrum Franken, Frauenklinik, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen–European Metropolitan area Nuremberg (CCC ER-EMN), Germany
- Christian M. Bayer MD
- Universitäts-Brustzentrum Franken, Frauenklinik, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen–European Metropolitan area Nuremberg (CCC ER-EMN), Germany
- Adib Jacob
- Novartis Pharma GmbH, Nuremberg, Germany
- Katja Schmidt PhD
- Novartis Pharma GmbH, Nuremberg, Germany
- Erik Belleville PhD
- Clin-Sol GmbH, Würzburg, Germany
- Peyman Hadji MD
- Krankenhaus Nordwest, Klinik für Gynäkologie und Geburtshilfe, Frankfurt, Germany
- Sara Y. Brucker MD
- Department für Frauengesundheit, Universitätsklinikum Tübingen, Eberhard-Karls-Universität, Tübingen, Germany
- Diethelm Wallwiener MD
- Department für Frauengesundheit, Universitätsklinikum Tübingen, Eberhard-Karls-Universität, Tübingen, Germany
- Sherko Kümmel MD
- Brustzentrum, Kliniken Essen Mitte, Evang. Huyssens-Stiftung/Knappschaft GmbH, Essen, Germany
- Matthias W. Beckmann MD
- Universitäts-Brustzentrum Franken, Frauenklinik, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen–European Metropolitan area Nuremberg (CCC ER-EMN), Germany
- Daniela Paepke MD
- Frauenklinik rechts der Isar, Technische Universität München, Munich, Germany
- DOI
- https://doi.org/10.1177/1534735416668575
- Journal volume & issue
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Vol. 16
Abstract
Background . Breast cancer patients often use complementary and alternative medicine, but few prospectively collected data on the topic are available specifically for postmenopausal breast cancer patients. A large prospective study was therefore conducted within a noninterventional study in order to identify the characteristics of patients interested in integrative medicine. Methods . The EvAluate-TM study is a prospective, multicenter noninterventional study in which treatment with the aromatase inhibitor letrozole was evaluated in postmenopausal women with hormone receptor–positive primary breast cancer. Between 2008 and 2009, 5045 postmenopausal patients were enrolled at 339 certified breast centers in Germany. As part of the data collection process, patients were asked at the baseline about their interest in and information needs relating to integrative medicine. Results . Of the 5045 patients recruited, 3411 responded to the questionnaire on integrative medicine and took part in the analysis, 1583 patients expressed an interest in integrative medicine, and 1828 patients declared no interest. Relevant predictors of interest in integrative medicine were age, body mass index, tumor size, previous chemotherapy, and use of concomitant medications for other medical conditions. Interest in integrative medicine declined highly significantly ( P 65 years, 38.0%). Patients in favor of integrative medicine were significantly less satisfied with the information received about individual treatments and antihormonal therapy. Patients with interest in integrative medicine were more often interested in rehabilitation and fitness, nutritional counseling, and additional support from self-help organizations. These women were mostly interested in receiving information about their disease and integrative medicine from a physician, rather than from other sources. Conclusions . This study shows that a considerable proportion of postmenopausal breast cancer patients are interested in integrative medicine. Information about integrative medicine should therefore be provided as part of patient care for this group. It was found that receiving concomitant medication for other medical conditions is one of the main predictors for women not being interested in integrative medicine. This group of patients may need special attention and individualized information about integrative medicine. Additionally, most patients were interested in obtaining the relevant information from their doctor.
