Cancer Stem Cell Research: Current Situation and Problems

Naoya Kobayashi M.D., Ph.D.; Nalú Navarro-Alvarez; Alejandro Soto-Gutierrez; Hironobu Kawamoto; Yoshitaka Kondo; Tomoki Yamatsuji; Yasuhiro Shirakawa; Yoshio Naomoto; Noriaki Tanaka

doi:10.3727/000000008783906982

Cell Transplantation (Jan 2008)

Cancer Stem Cell Research: Current Situation and Problems

Naoya Kobayashi M.D., Ph.D.,
Nalú Navarro-Alvarez,
Alejandro Soto-Gutierrez,
Hironobu Kawamoto,
Yoshitaka Kondo,
Tomoki Yamatsuji,
Yasuhiro Shirakawa,
Yoshio Naomoto,
Noriaki Tanaka

Affiliations

Naoya Kobayashi M.D., Ph.D.: Department of Gastroenterological Surgery, Transplant and Surgical Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
Nalú Navarro-Alvarez: Department of Gastroenterological Surgery, Transplant and Surgical Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
Alejandro Soto-Gutierrez: Department of Gastroenterological Surgery, Transplant and Surgical Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
Hironobu Kawamoto: Department of Gastroenterological Surgery, Transplant and Surgical Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
Yoshitaka Kondo: Department of Gastroenterological Surgery, Transplant and Surgical Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
Tomoki Yamatsuji: Department of Gastroenterological Surgery, Transplant and Surgical Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
Yasuhiro Shirakawa: Department of Gastroenterological Surgery, Transplant and Surgical Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
Yoshio Naomoto: Department of Gastroenterological Surgery, Transplant and Surgical Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan
Noriaki Tanaka: Department of Gastroenterological Surgery, Transplant and Surgical Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama 700-8558, Japan

DOI: https://doi.org/10.3727/000000008783906982
Journal volume & issue: Vol. 17

Abstract

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The concept of a “cancer stem cell system” that continues to supply cancer component cells has been proposed. It is time to apply stem cell studies, which is a field of expertise in regenerative medicine, to cancer treatment. Cancer treatments that effectively attack cancer stem cells acting as a manufacturing plant for producing differentiated cancer progenies will be designed by revealing the cancer stem cell system. Therefore, in the near future we hope that revolution will occur in cancer therapy to eradicate cancer and prevent the recurrence thereof. In this review we discuss the current situation and problems of cancer stem cell research.

Published in Cell Transplantation

ISSN: 0963-6897 (Print); 1555-3892 (Online)
Publisher: SAGE Publishing
Country of publisher: United States
LCC subjects: Medicine
Website: http://journals.sagepub.com/home/cll

About the journal