(<i>R</i>)-(+)-3,5-Dinitro-<i>N</i>-(1-phenylethyl)benzothioamide

Abstract

(R)-(+)-3,5-dinitro-N-(1-phenylethyl)benzothioamide 1 is a potential chiral solvating agent (CSA) for the spectral resolution of enantiomers via 1H NMR spectroscopy. The single enantiomer of 1 was synthesized from commercially available (R)-(+)-a-methylbenzylamine 2 in two steps with 85% yield.

Keywords

• benzylamine
• chiral solvating agent
• thioamide