Research Results in Pharmacology (Jun 2016)

PHARMACOKINETIC STUDIES DERIVED INDOLE SS-68 WITH ANTIARRHYTHMIC AND ANTIANGINAL PROPERTIES

  • Pavel Galenko-Yaroshevsky,
  • Alexandr Kulikov,
  • Dmitry Vinakov,
  • Tatyana Avtina,
  • Konstantin Suzdalev,
  • Mikhail Pokrovskii

DOI
https://doi.org/10.18413/2313-8971-2016-2-2-20-24
Journal volume & issue
Vol. 2, no. 2
pp. 20 – 24

Abstract

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A method of quantitative determination of SS-68 derivative of indole in rabbit blood plasma by high performance liquid chromatography with tandem mass spectrometric detector (HPLCMS/MS). Conducted pharmacokinetic studies SS-68 in the body of rabbits. Set the main pharmacokinetic parameters of the substance that allow you to optimize the future use of it’s as a potential drug in cardiology practice.

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