Advanced Ultrasound in Diagnosis and Therapy (Dec 2024)

Precision Imaging for Prostate Cancer Localization: How Multiparametric Ultrasound Stands Against Multiparametric MRI

  • Amr Mohammed, MD, Priscilla Machado, MD, Tania Siu Xiao, MD, Aylin Tahmasebi, MD, Mostafa Alnoury, MD, Edouard Trabulsi, MD, Ethan J. Halpern, MD, John R. Eisenbrey, PhD, Flemming Forsberg, PhD

DOI
https://doi.org/10.37015/AUDT.2024.240047
Journal volume & issue
Vol. 8, no. 4
pp. 217 – 230

Abstract

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Multiparametric MRI (mpMRI) is currently the standard imaging modality for the diagnosis of prostate cancer; however, studies have reported that targeted biopsy based on mpMRI may miss approximately 30% of clinically significant cases. Recent advances in ultrasound imaging have improved its accuracy for detection of prostate cancer. Newer techniques such as MicroUS, elastography, contrast-enhanced ultrasound (CEUS), and contrast ultrasound dispersion imaging (CUDI) have enabled a comprehensive, real-time, and relatively inexpensive approach to evaluate the prostate gland. Multiparametric ultrasound (mpUS) integrates multiple parameters from these techniques to generate multiparametric maps akin to those produced by mpMRI, to localize prostate cancer. This review aims to explore the performance of modern ultrasound techniques and mpUS for diagnosis of prostate cancer, comparing them with mpMRI.

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